So maybe the crowd (such as it is) can help me with this one. I’ve been racking my brain and scouring Google to come up with some good examples - hell, any examples - of pharmacogenomics in practice, right now. I mean, this is the supposed Holy Grail of personalized medicine - that drugs will be tailored to our genomes - and there has been a good 20 years research. But I can only find two examples: Herceptin, which is used in breast cancer patients whose cancer is caused by excessive protein from the HER2 gene; and warfarin, a blood-thinning drug used for patients recovering from heart attack or major surgery - there’s now a screening test for those with certain gene that causes excess bleeding, raising the possibility of serious side effects (stroke, etc).
But really, that’s it? I mean it’s 2007, and this is the big payoff of personalized medicine, which we’ve been hearing about for a decade - two lousy drugs?
Tell me if I’m wrong (I sure hope I am…)